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How does information circulate in the nervous system? How does the nerve impulse start, how does it travel along axons, and how is it transmitted (or not) from one neuron to the next? Thanks to this MOOC, you will master these basic principles of neuronal physiology.

This MOOC is especially intended for students in biological sciences, high school science teachers, graduate students, research assistants and researchers who want to understand electrophysiology basics.

With an emphasis on the experimental approach, this course will address:

• the transmembrane ion gradients and the membrane potential that control the movement of ions across the neuronal membrane. These ion movements create ion currents;
• the genesis of the sodium action potential and its propagation to the axonal terminals;
• the function of the synapse: neurotransmitter release, postsynaptic glutamate and GABA receptors, postsynaptic currents and their integration.

I would like to thank Isabelle Virard & Marine Chabrolin without whom all this would not have been possible.

To see the course

Every week, the chapter includes:

• didactic short videos presenting cellular neurophysiology
• videos of experiments preformed in a research laboratory

Aix Marseille University and the Mediterranean Institute of Neurobiology (INMED), an INSERM laboratory, created this MOOC in neurophysiology, thanks to an A*MIDEX funding.